L36S (p.Leu36Ser) variant of MCL1 (Q07820)
L36S (p.Leu36Ser) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
L36S (p.Leu36Ser) variant details
- p.Leu36Ser
- Ensembl rs1570984004
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.07
- CADD 12.60
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available