L21F (p.Leu21Phe) variant of MCL1 (Q07820)
L21F (p.Leu21Phe) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
L21F (p.Leu21Phe) variant details
- p.Leu21Phe
- ExAC rs751612946
- TOPMed rs751612946
- gnomAD rs751612946
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- REVEL 0.07
- CADD 16.50
- PolyPhen-2 0.44
- SIFT 0.03
- Population evidence available
- Structural context available