L14V (p.Leu14Val) variant of MCL1 (Q07820)
L14V (p.Leu14Val) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
L14V (p.Leu14Val) variant details
- p.Leu14Val
- 1000Genomes rs587612386
- ExAC rs587612386
- TOPMed rs587612386
- gnomAD rs587612386
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.09
- CADD 23.80
- PolyPhen-2 0.10
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available