L14F (p.Leu14Phe) variant of MCL1 (Q07820)
L14F (p.Leu14Phe) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
L14F (p.Leu14Phe) variant details
- p.Leu14Phe
- 1000Genomes rs587612386
- ExAC rs587612386
- TOPMed rs587612386
- gnomAD rs587612386
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.08
- CADD 24.10
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the 1KG:PJL population (allele frequency 0.0052)
- Structural context available