I57M (p.Ile57Met) variant of MCL1 (Q07820)
I57M (p.Ile57Met) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
I57M (p.Ile57Met) variant details
- p.Ile57Met
- ExAC rs758996875
- TOPMed rs758996875
- gnomAD rs758996875
- Missense
- Variant Prioritization Score for Impact Estimate 0.0911
- REVEL 0.07
- CADD 9.05
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9.5e-07)
- Structural context available