G59E (p.Gly59Glu) variant of MCL1 (Q07820)
G59E (p.Gly59Glu) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G59E (p.Gly59Glu) variant details
- p.Gly59Glu
- cosmic curated COSV57189
- gnomAD rs1647977930
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.17
- CADD 20.00
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available