G58V (p.Gly58Val) variant of MCL1 (Q07820)
G58V (p.Gly58Val) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G58V (p.Gly58Val) variant details
- p.Gly58Val
- ExAC rs773949054
- TOPMed rs773949054
- gnomAD rs773949054
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.16
- CADD 19.40
- PolyPhen-2 0.54
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available