G58C (p.Gly58Cys) variant of MCL1 (Q07820)
G58C (p.Gly58Cys) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G58C (p.Gly58Cys) variant details
- p.Gly58Cys
- Ensembl rs2101700240
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.13
- CADD 23.40
- PolyPhen-2 0.82
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 3.8e-05)
- Structural context available