G51V (p.Gly51Val) variant of MCL1 (Q07820)
G51V (p.Gly51Val) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
G51V (p.Gly51Val) variant details
- p.Gly51Val
- ExAC rs753664661
- gnomAD rs753664661
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.04
- CADD 23.10
- PolyPhen-2 0.02
- SIFT 0.05
- Most common in the East Asian population (allele frequency 2.9e-05)
- Structural context available