G51A (p.Gly51Ala) variant of MCL1 (Q07820)
G51A (p.Gly51Ala) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
G51A (p.Gly51Ala) variant details
- p.Gly51Ala
- ExAC rs753664661
- gnomAD rs753664661
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.02
- CADD 19.10
- PolyPhen-2 0.10
- SIFT 0.54
- Most common in the East Asian population (allele frequency 2.9e-05)
- Structural context available