G49R (p.Gly49Arg) variant of MCL1 (Q07820)
G49R (p.Gly49Arg) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
G49R (p.Gly49Arg) variant details
- p.Gly49Arg
- cosmic curated COSV57190
- gnomAD rs1312773225
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.20
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 3.2e-05)
- Structural context available