G49E (p.Gly49Glu) variant of MCL1 (Q07820)
G49E (p.Gly49Glu) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G49E (p.Gly49Glu) variant details
- p.Gly49Glu
- ExAC rs757542528
- TOPMed rs757542528
- gnomAD rs757542528
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.24
- CADD 24.00
- PolyPhen-2 1.00
- SIFT 0.08
- Population evidence available
- Structural context available