G49A (p.Gly49Ala) variant of MCL1 (Q07820)
G49A (p.Gly49Ala) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
G49A (p.Gly49Ala) variant details
- p.Gly49Ala
- ExAC rs757542528
- TOPMed rs757542528
- gnomAD rs757542528
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.16
- CADD 23.40
- PolyPhen-2 0.99
- SIFT 0.26
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available