G3D (p.Gly3Asp) variant of MCL1 (Q07820)
G3D (p.Gly3Asp) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
G3D (p.Gly3Asp) variant details
- p.Gly3Asp
- TOPMed rs1647992648
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.11
- CADD 22.50
- PolyPhen-2 0.47
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available