G33E (p.Gly33Glu) variant of MCL1 (Q07820)
G33E (p.Gly33Glu) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
G33E (p.Gly33Glu) variant details
- p.Gly33Glu
- TOPMed rs902324572
- gnomAD rs902324572
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.01
- CADD 13.60
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available