G32E (p.Gly32Glu) variant of MCL1 (Q07820)
G32E (p.Gly32Glu) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
G32E (p.Gly32Glu) variant details
- p.Gly32Glu
- cosmic curated COSV57190
- ExAC rs770152297
- TOPMed rs770152297
- gnomAD rs770152297
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.04
- CADD 16.60
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available