G27D (p.Gly27Asp) variant of MCL1 (Q07820)
G27D (p.Gly27Asp) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G27D (p.Gly27Asp) variant details
- p.Gly27Asp
- TOPMed rs936472592
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.10
- CADD 23.20
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available