G26S (p.Gly26Ser) variant of MCL1 (Q07820)
G26S (p.Gly26Ser) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
G26S (p.Gly26Ser) variant details
- p.Gly26Ser
- gnomAD rs925013521
- Missense
- Variant Prioritization Score for Impact Estimate 0.124
- REVEL 0.02
- CADD 16.30
- PolyPhen-2 0.01
- SIFT 0.07
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available