G24S (p.Gly24Ser) variant of MCL1 (Q07820)
G24S (p.Gly24Ser) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
G24S (p.Gly24Ser) variant details
- p.Gly24Ser
- ExAC rs761537521
- gnomAD rs761537521
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.05
- CADD 16.60
- PolyPhen-2 0.08
- SIFT 0.16
- Most common in the South Asian population (allele frequency 2.4e-05)
- Structural context available