G22E (p.Gly22Glu) variant of MCL1 (Q07820)
G22E (p.Gly22Glu) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
G22E (p.Gly22Glu) variant details
- p.Gly22Glu
- ExAC rs766507232
- gnomAD rs766507232
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.12
- CADD 15.70
- PolyPhen-2 0.13
- SIFT 0.01
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available