G22A (p.Gly22Ala) variant of MCL1 (Q07820)
G22A (p.Gly22Ala) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
G22A (p.Gly22Ala) variant details
- p.Gly22Ala
- ExAC rs766507232
- gnomAD rs766507232
- Missense
- Variant Prioritization Score for Impact Estimate 0.0975
- REVEL 0.07
- CADD 8.51
- PolyPhen-2 0.00
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 1.4e-05)
- Structural context available