G17W (p.Gly17Trp) variant of MCL1 (Q07820)
G17W (p.Gly17Trp) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G17W (p.Gly17Trp) variant details
- p.Gly17Trp
- TOPMed rs932863734
- gnomAD rs932863734
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- REVEL 0.25
- CADD 28.30
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available