G17V (p.Gly17Val) variant of MCL1 (Q07820)
G17V (p.Gly17Val) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
G17V (p.Gly17Val) variant details
- p.Gly17Val
- TOPMed rs1012747207
- gnomAD rs1012747207
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.19
- CADD 23.20
- PolyPhen-2 0.05
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available