G17R (p.Gly17Arg) variant of MCL1 (Q07820)
G17R (p.Gly17Arg) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
G17R (p.Gly17Arg) variant details
- p.Gly17Arg
- TOPMed rs932863734
- gnomAD rs932863734
- Missense
- Variant Prioritization Score for Impact Estimate 0.456
- REVEL 0.23
- CADD 26.70
- PolyPhen-2 0.84
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available