G17E (p.Gly17Glu) variant of MCL1 (Q07820)
G17E (p.Gly17Glu) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
G17E (p.Gly17Glu) variant details
- p.Gly17Glu
- cosmic curated COSV57190
- TOPMed rs1012747207
- gnomAD rs1012747207
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.23
- CADD 25.20
- PolyPhen-2 0.79
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available