G17A (p.Gly17Ala) variant of MCL1 (Q07820)
G17A (p.Gly17Ala) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
G17A (p.Gly17Ala) variant details
- p.Gly17Ala
- TOPMed rs1012747207
- gnomAD rs1012747207
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.12
- CADD 23.20
- PolyPhen-2 0.29
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.7e-05)
- Structural context available