F2L (p.Phe2Leu) variant of MCL1 (Q07820)
F2L (p.Phe2Leu) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
F2L (p.Phe2Leu) variant details
- p.Phe2Leu
- gnomAD rs1465779538
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- REVEL 0.04
- CADD 19.90
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available