E47D (p.Glu47Asp) variant of MCL1 (Q07820)
E47D (p.Glu47Asp) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
E47D (p.Glu47Asp) variant details
- p.Glu47Asp
- cosmic curated COSV57191
- Ensembl rs2101700422
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.05
- CADD 15.10
- PolyPhen-2 0.00
- SIFT 0.14
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available