E41K (p.Glu41Lys) variant of MCL1 (Q07820)
E41K (p.Glu41Lys) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
E41K (p.Glu41Lys) variant details
- p.Glu41Lys
- TOPMed rs898520253
- gnomAD rs898520253
- Missense
- Variant Prioritization Score for Impact Estimate 0.347
- REVEL 0.09
- CADD 22.90
- PolyPhen-2 0.14
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 0.00024)
- Structural context available