A8V (p.Ala8Val) variant of MCL1 (Q07820)
A8V (p.Ala8Val) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
A8V (p.Ala8Val) variant details
- p.Ala8Val
- cosmic curated COSV57191
- gnomAD rs1445925900
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.13
- CADD 24.20
- PolyPhen-2 0.22
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available