A8G (p.Ala8Gly) variant of MCL1 (Q07820)
A8G (p.Ala8Gly) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
A8G (p.Ala8Gly) variant details
- p.Ala8Gly
- gnomAD rs1445925900
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.09
- CADD 24.40
- PolyPhen-2 0.41
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available