A55V (p.Ala55Val) variant of MCL1 (Q07820)
A55V (p.Ala55Val) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A55V (p.Ala55Val) variant details
- p.Ala55Val
- ExAC rs775581615
- TOPMed rs775581615
- gnomAD rs775581615
- Missense
- Variant Prioritization Score for Impact Estimate 0.113
- REVEL 0.03
- CADD 8.85
- PolyPhen-2 0.03
- SIFT 0.25
- Most common in the Latino/Admixed American population (allele frequency 9e-05)
- Structural context available