A55E (p.Ala55Glu) variant of MCL1 (Q07820)
A55E (p.Ala55Glu) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A55E (p.Ala55Glu) variant details
- p.Ala55Glu
- ExAC rs775581615
- TOPMed rs775581615
- gnomAD rs775581615
- Missense
- Variant Prioritization Score for Impact Estimate 0.105
- REVEL 0.03
- CADD 6.97
- PolyPhen-2 0.00
- SIFT 0.42
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available