A44T (p.Ala44Thr) variant of MCL1 (Q07820)
A44T (p.Ala44Thr) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A44T (p.Ala44Thr) variant details
- p.Ala44Thr
- ExAC rs758423754
- TOPMed rs758423754
- gnomAD rs758423754
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.06
- CADD 14.80
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available