A44S (p.Ala44Ser) variant of MCL1 (Q07820)
A44S (p.Ala44Ser) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A44S (p.Ala44Ser) variant details
- p.Ala44Ser
- ExAC rs758423754
- TOPMed rs758423754
- gnomAD rs758423754
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.03
- CADD 13.20
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available