A42P (p.Ala42Pro) variant of MCL1 (Q07820)
A42P (p.Ala42Pro) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
A42P (p.Ala42Pro) variant details
- p.Ala42Pro
- ExAC rs373644818
- TOPMed rs373644818
- gnomAD rs373644818
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.05
- CADD 22.30
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the Middle Eastern population (allele frequency 0.00018)
- Structural context available