A28P (p.Ala28Pro) variant of MCL1 (Q07820)
A28P (p.Ala28Pro) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A28P (p.Ala28Pro) variant details
- p.Ala28Pro
- ExAC rs768684341
- TOPMed rs768684341
- gnomAD rs768684341
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.16
- CADD 22.70
- PolyPhen-2 0.45
- SIFT 0.25
- Most common in the South Asian population (allele frequency 0.00018)
- Structural context available