A23V (p.Ala23Val) variant of MCL1 (Q07820)
A23V (p.Ala23Val) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A23V (p.Ala23Val) variant details
- p.Ala23Val
- ExAC rs750616819
- gnomAD rs750616819
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.04
- CADD 20.20
- PolyPhen-2 0.06
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available