A19P (p.Ala19Pro) variant of MCL1 (Q07820)
A19P (p.Ala19Pro) in MCL1 (Q07820) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A19P (p.Ala19Pro) variant details
- p.Ala19Pro
- TOPMed rs1249841412
- gnomAD rs1249841412
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.09
- CADD 20.60
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available