M91I (p.Met91Ile) variant of MCCC1 (Q96RQ3)
M91I (p.Met91Ile) in MCCC1 (Q96RQ3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
M91I (p.Met91Ile) variant details
- p.Met91Ile
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.812
- REVEL 0.79
- CADD 34.00
- PolyPhen-2 0.75
- SIFT 0.02
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available