Y41H (p.Tyr41His) variant of MC4R (Melanocortin receptor 4)
Y41H (p.Tyr41His) in MC4R (Melanocortin receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
Y41H (p.Tyr41His) variant details
- p.Tyr41His
- gnomAD 18-60372229-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.20
- MetaLR 0.11
- MetaSVM -0.99
- CADD 23.20
- PolyPhen-2 0.59
- SIFT 0.50
- Population evidence available
- Structural context available
- Literature evidence available