W16R (p.Trp16Arg) variant of MC4R (Melanocortin receptor 4)
W16R (p.Trp16Arg) in MC4R (Melanocortin receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
W16R (p.Trp16Arg) variant details
- p.Trp16Arg
- gnomAD 18-60372304-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.13
- MetaLR 0.07
- MetaSVM -1.06
- CADD 21.40
- PolyPhen-2 0.00
- SIFT 0.60
- Population evidence available
- Structural context available
- Literature evidence available