S4S (p.Ser4Ser) variant of MC4R (Melanocortin receptor 4)
S4S (p.Ser4Ser) in MC4R (Melanocortin receptor 4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
S4S (p.Ser4Ser) variant details
- p.Ser4Ser
- rs757561015
- gnomAD 18-60372338-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.123
- CADD 6.02
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available
- Literature evidence available