N26K (p.Asn26Lys) variant of MC4R (Melanocortin receptor 4)
N26K (p.Asn26Lys) in MC4R (Melanocortin receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
N26K (p.Asn26Lys) variant details
- p.Asn26Lys
- gnomAD rs1371133103
- Missense
- Variant Prioritization Score for Impact Estimate 0.0676
- REVEL 0.02
- MetaLR 0.05
- MetaSVM -1.06
- CADD 1.66
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available