N26D (p.Asn26Asp) variant of MC4R (Melanocortin receptor 4)
N26D (p.Asn26Asp) in MC4R (Melanocortin receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
N26D (p.Asn26Asp) variant details
- p.Asn26Asp
- TOPMed rs1375424360
- gnomAD rs1375424360
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.02
- MetaLR 0.06
- MetaSVM -1.06
- CADD 22.20
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available