M9V (p.Met9Val) variant of MC4R (Melanocortin receptor 4)
M9V (p.Met9Val) in MC4R (Melanocortin receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
M9V (p.Met9Val) variant details
- p.Met9Val
- gnomAD 18-60372325-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.10
- MetaLR 0.07
- MetaSVM -1.05
- CADD 11.00
- PolyPhen-2 0.00
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available