M9T (p.Met9Thr) variant of MC4R (Melanocortin receptor 4)
M9T (p.Met9Thr) in MC4R (Melanocortin receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
M9T (p.Met9Thr) variant details
- p.Met9Thr
- gnomAD 18-60372324-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.109
- REVEL 0.06
- MetaLR 0.05
- MetaSVM -1.06
- CADD 8.48
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available