L60L (p.Leu60Leu) variant of MC4R (Melanocortin receptor 4)
L60L (p.Leu60Leu) in MC4R (Melanocortin receptor 4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
L60L (p.Leu60Leu) variant details
- p.Leu60Leu
- rs1439366696
- gnomAD 18-60372170-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.435
- CADD 9.75
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available
- Literature evidence available