L59L (p.Leu59Leu) variant of MC4R (Melanocortin receptor 4)
L59L (p.Leu59Leu) in MC4R (Melanocortin receptor 4) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
L59L (p.Leu59Leu) variant details
- p.Leu59Leu
- gnomAD 18-60372173-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.27
- CADD 8.31
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available