L13P (p.Leu13Pro) variant of MC4R (Melanocortin receptor 4)
L13P (p.Leu13Pro) in MC4R (Melanocortin receptor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
L13P (p.Leu13Pro) variant details
- p.Leu13Pro
- gnomAD 18-60372312-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.209
- REVEL 0.11
- MetaLR 0.12
- MetaSVM -1.01
- CADD 24.20
- PolyPhen-2 0.61
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available